---
author:
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  family: Edmunds
  given: Scott
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date: '2017-09-14T00:00:00+00:00'
date_updated: '2025-12-06T10:32:30+00:00'
guid: http://gigasciencejournal.com/blog/?p=2125
identifier: https://doi.org/10.59350/t4pe9-4es23
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summary: '*As a journal focussed on open science we are big promoters of research
  parasites (and research on parasites), and try to feeds them with open data and
  tools. It is therefore appropriate this is the second year GigaScience has supported
  and sponsored the Research Parasite awards.'
title: Research Parasites Wanted. Q&A with Casey Greene & Brian Byrd
url: https://wayback.archive-it.org/22098/2025-05-01T17:13:42Z/http://gigasciencejournal.com/blog/research-parasites-wanted-qa-with-casey-greene
version: v1
---

\*![](http://gigasciencejournal.com/blog/wp-content/uploads/2017/09/Screen-Shot-2017-09-07-at-09.44.38-300x300.png){.wp-image-2126
.alignright loading="lazy" decoding="async"
srcset="http://gigasciencejournal.com/blog/wp-content/uploads/2017/09/Screen-Shot-2017-09-07-at-09.44.38-300x300.png 300w, http://gigasciencejournal.com/blog/wp-content/uploads/2017/09/Screen-Shot-2017-09-07-at-09.44.38-150x150.png 150w, http://gigasciencejournal.com/blog/wp-content/uploads/2017/09/Screen-Shot-2017-09-07-at-09.44.38-768x768.png 768w, http://gigasciencejournal.com/blog/wp-content/uploads/2017/09/Screen-Shot-2017-09-07-at-09.44.38-1024x1024.png 1024w, http://gigasciencejournal.com/blog/wp-content/uploads/2017/09/Screen-Shot-2017-09-07-at-09.44.38.png 1532w"
sizes="(max-width: 305px) 100vw, 305px" width="305" height="305"}As a
journal focussed on open science we are big promoters of research
parasites ([and research on
parasites](http://gigasciencejournal.com/blog/reproducible-research-resources-researching-parasites/)),
and try to feeds them with open data and tools. It is therefore
appropriate this is the second year GigaScience has supported and
sponsored the Research Parasite awards. In one of our
[Q&As](http://gigasciencejournal.com/blog/tag/qa/), organisers Casey
Greene and Brian Byrd tell us about the awards, how they came about, and
you can become a tropical research parasite by winning a travel grant to
the [Pacific Symposium on Biocomputing](http://psb.stanford.edu/) in
Hawaii.\
\*\
*Casey Greene (CG) is an Assistant Professor of Systems Pharmacology and
Translational Therapeutics in the Perelman School of Medicine at the
University of Pennsylvania. His lab develops deep learning methods that
integrate distinct large-scale datasets to extract the rich and
intrinsic information embedded in such integrated data. J. Brian Byrd
(JBB) is an NIH-funded physician-scientist interested in high blood
pressure. His lab focuses on the clinical investigation of hypertension,
using proof of concept clinical trials, among other types of studies. In
addition, Dr. Byrd was an investigator for the SYMPLICITY-3 HTN pivotal
clinical trial of renal artery denervation for treatment-resistant high
blood pressure.*

**Tell us about the parasite award. What inspired you to set it up? What
sort of parasites are you looking for, and what can they win?**

**CG:** I, like many scientists, was annoyed at the tone of the [Longo
and Drazen
editorial](http://www.nejm.org/doi/full/10.1056/NEJMe1516564). The
behaviors that were described as parasitic, namely reanalyzing data and
potentially arriving at different conclusions, struck me as central to
the practice of good science and exactly what we try to teach students
at many phases of their training. Identifying a distinct interpretation
that is compatible with existing data is often an excellent start to a
qualifier exam. [Iddo Friedberg
tweeted](https://twitter.com/iddux/status/690563238979723267) a joke
about a research parasite award. It struck me as an excellent
opportunity to encourage, as opposed to discourage, these types of
behaviors, so I was happy to work to make it a reality.

> I propose a new science award: \"The Research Parasite Award is given
> to those who used someone else\'s data to do some really cool sh\*t\"
>
> --- Iddo Friedberg (@iddux) [January 22,
> 2016](https://twitter.com/iddux/status/690563238979723267)

For this award we\'re looking for scientists who have analyzed someone
else\'s data and published their findings independently of the data
generators. Our goal with the award was to reward precisely the approach
to science that was decried by the [\"Research Parasites\"
editorial](http://www.nejm.org/doi/full/10.1056/NEJMe1516564).
Candidates came from many fields, which really excited us, as we have a
very broad definition of Research Parasites. We view the term \"Research
Parasite\" as entirely complementary in this context, and we
specifically want to encourage individuals who identify with groups that
are underrepresented in their field to apply.

::: {#attachment_2130 .wp-caption .alignleft style="width: 381px"}
![](http://gigasciencejournal.com/blog/wp-content/uploads/2017/09/caseypic-300x200.jpg){.wp-image-2130
loading="lazy" decoding="async"
aria-describedby="caption-attachment-2130"
srcset="http://gigasciencejournal.com/blog/wp-content/uploads/2017/09/caseypic-300x200.jpg 300w, http://gigasciencejournal.com/blog/wp-content/uploads/2017/09/caseypic-768x512.jpg 768w, http://gigasciencejournal.com/blog/wp-content/uploads/2017/09/caseypic-1024x683.jpg 1024w"
sizes="(max-width: 371px) 100vw, 371px" width="371" height="248"}

Casey lamprey modelling. Photo:Graham Perry
:::

There are two Research Parasite awards this year. The Senior Parasite
will receive a leather lamprey with a magnetic head that they can stick
to any ferromagnetic surface. The Junior Parasite will receive this
lamprey, as well as a \$500 cash prize and \$2950 in travel support to
attend [PSB](http://psb.stanford.edu/). We estimate that this is
sufficient to cover airfare from much of the world as well as hotel
costs for enough nights to receive the award.

\*\*\
As this is the second year of the competition how was last years award
received and who won it? Were nominees proud to be parasites, and did
the people who coined the term \"parasites\" get or respond to the
joke?\*\*

**CG:** The winners were Kun-Hsing Yu and Erick Turner. As committee
members we enjoyed reading all of the applications, and the decision was
extremely difficult. We\'ve got short bios of the winners plus their
work on our website, <http://researchparasite.com>. The nominees were
clearly proud parasites, which made us happy to see.

Last years award seemed to be well received. Dr. Jeff Drazen, one of the
authors of the editorial in question, was a good sport and attended PSB
and answered our questions immediately prior to the award presentation.
It\'s always hard to say what others find funny, but I think Jeff
understands where we were coming from with the award. I think that we
both would be happy to move beyond the negative research parasite term,
to more positively recognize the exemplars of science enabled by open
data.

**Were there any interesting lessons you learned from doing this, and
what are you doing differently this year? Tell us about the \"symbiont\"
award?**

**CG:** We had a wonderful time doing the awards, but it was a learning
process for us as well. We enjoyed reading the applications that were
submitted, and the serious purpose but tongue-in-cheek nature of the
awards led to some great application letters. I enjoyed hearing the
perspective of our winners during the awards ceremony. I would like to
see us record the ceremony this year (this reminds me that I need to
contact the PSB organizers!) so that it can be widely shared, including
to those who are unable to attend the meeting.

On the negative side, we were disappointed that we didn\'t
simultaneously recognize those who had shared data in ways that
encouraged independent reuse. In retrospect, this was an oversight on
our part. We decided to start a \"host\" award for those who were
exemplars in data sharing. However, we found that the terminology
wasn\'t quite right, because often the individuals whose data were
reused were not negatively affected by the reuse. We searched for a term
for a bit, and ended up settling on the term \"symbiont\" that refers to
organisms that live together. The relationship can be mutually
beneficial because it increases the scientific impact of those
investigators, so we moved a away from the term \"host\" even though it
breaks the symmetry with the Parasite Awards. The website for the
Research Symbiont Awards is <http://researchsymbionts.org>.

**![](http://gigasciencejournal.com/blog/wp-content/uploads/2017/09/JBB-Photo-236x300.jpg){.alignleft
.size-medium .wp-image-2127 loading="lazy" decoding="async"
srcset="http://gigasciencejournal.com/blog/wp-content/uploads/2017/09/JBB-Photo-236x300.jpg 236w, http://gigasciencejournal.com/blog/wp-content/uploads/2017/09/JBB-Photo-768x978.jpg 768w, http://gigasciencejournal.com/blog/wp-content/uploads/2017/09/JBB-Photo-804x1024.jpg 804w, http://gigasciencejournal.com/blog/wp-content/uploads/2017/09/JBB-Photo.jpg 855w"
sizes="(max-width: 236px) 100vw, 236px" width="236" height="300"}JBB:**
I\'m a clinical investigator, and in that role, I run a laboratory & I
have been directly involved in clinical trials. As Casey and I got to
know each other, I shared my hope that something could be done to
recognize people who generate data and share the data. Casey & I share
the vision that data sharing is good for many reasons, and I am happy to
be the inaugural Chair of the Symbiont Awards Committee. The committee
is a diverse group with keen insight, and we look forward to selecting
the awardees. We have two awards for people who have shared data above
and beyond what is expected in their field. We have an award for an
early career researcher involved in human health research, and one for a
more senior researcher, who can be working in any scientific discipline.
We hope the Symbiont Awards help nudge the culture of researchers toward
more data sharing, and we are excited about the opportunity to recognize
those who already are setting the standard.

**As an open science/open data journal we try our best to help feed and
support the research parasite community, at the same time as giving
credit and sustenance to their hosts. Is there anything we and other
journals could and should be doing to help this process even more?**

**CG:** One of the things that we\'ve seen is that researchers can
resist openly sharing their data for a number of reasons. One concern
that we hear frequently is that someone might download data and analyze
it without fully understanding its nuances, leading some of those
performing re-analyses to make findings that are trivial or incorrect.
[We\'d support a
mechanism](http://www.nejm.org/doi/full/10.1056/NEJMc1705477) that
encourages authors of highly re-used datasets to write periodic reviews
to summarize the findings of reanalyses . This would also provide an
opportunity to independently weigh in on these efforts.

Of course, making it as easy as possible for researchers engaged in
reanalysis to directly recognize the datasets that they used in their
work is important. Right now, this is primarily done via citation.
However, some journals limit the number of references that can be used
in a given manuscript. I\'d encourage journals to do away with these
reference limits and to concurrently work on supporting the option more
granular citation forms, which could enable researchers to separately
note the source of data, ideas, software, and other elements.

**Fortunately we [promote
citation](http://gigasciencejournal.com/blog/having-a-finger-on-the-pulse-of-data-citation/)
of all research objects (data, software, workflows, etc.)  and encourage
the inclusion of as much technical detail as possible in the body of
manuscripts.\
![](http://gigasciencejournal.com/blog/wp-content/uploads/2017/09/Screen-Shot-2017-09-14-at-21.01.46-1024x490.png){.aligncenter
.wp-image-2131 loading="lazy" decoding="async"
srcset="http://gigasciencejournal.com/blog/wp-content/uploads/2017/09/Screen-Shot-2017-09-14-at-21.01.46-1024x490.png 1024w, http://gigasciencejournal.com/blog/wp-content/uploads/2017/09/Screen-Shot-2017-09-14-at-21.01.46-300x144.png 300w, http://gigasciencejournal.com/blog/wp-content/uploads/2017/09/Screen-Shot-2017-09-14-at-21.01.46-768x368.png 768w"
sizes="(max-width: 681px) 100vw, 681px" width="681" height="326"}What is
the plan for the awards beyond 2018, and do you have any final thoughts
on this type of process?**

**CG:** We\'ve received some generous financial gifts for these Awards
for Rigorous Secondary Data Analysis (colloquially called the Parasite
and Symbiont awards). These gifts have allowed us to establish an
endowment that will, starting with the 2019 award year, provide modest
prizes to recipients. If anyone would like to help us recognize data
sharing and reuse, we\'d be happy to work with them and we have a URL
available for gifts to this fund:
<https://giving.apps.upenn.edu/giving/jsp/fast.do?fastStart=simpleForm&program=MED&fund=404893&bhcp=1>

In closing, I want to note that we\'ve really enjoyed putting together
these awards. We think there\'s a very nice opportunity for copycat or
franchised awards at the society level. We\'d love to see communities
build awards to specifically acknowledge their own exemplars of data
reuse and data sharing. The applications that we receive are quite
broad, and I\'m sure that there are many societies who could find great
Parasites and Symbionts in their midst. I guess what I\'m really saying
is that we\'d like to see the \"Research Parasite Award\"-Parasites get
their acts together!\*\
\*

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