---
author:
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  family: Edmunds
  given: Scott
  url: https://orcid.org/0000-0001-6444-1436
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container: GigaBlog
date: '2020-03-01T00:00:00+00:00'
date_updated: '2025-12-06T10:19:55+00:00'
guid: http://gigasciencejournal.com/blog/?p=3242
identifier: https://doi.org/10.59350/58bc0-vq111
image: http://gigasciencejournal.com/blog/wp-content/uploads/2020/03/EOA21wPUYAEnCJ9-300x225.jpg
images:
- alt: Plant and Animal Genomes under construction
  height: '225'
  sizes: '(max-width: 300px) 100vw, 300px'
  src: http://gigasciencejournal.com/blog/wp-content/uploads/2020/03/EOA21wPUYAEnCJ9-300x225.jpg
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issn: null
keywords:
- Biology
- Conferences
- G10K
- Genomics
- Plant Genomics
lang: en
license: https://creativecommons.org/licenses/by/4.0/legalcode
rid: 5rwkt-crb74
rights: https://creativecommons.org/licenses/by/4.0/legalcode
summary: As publishers of a lot of plant and animal genomes, the biggest conference
  for this research community is the appropriately named Plant and Animal Genome Conference
  (PAG). We've attended a number of these giant meetings in their San Diego base,
  and in recent years they have been branching out to host satellites in Asia (PAG
  Asia, which last year included a workshop that we participated in). And we attended
  the 28 <sup> th </sup> edition of the
title: 'Under Construction: Plant and Animal Genomes Get a Refurb'
url: https://wayback.archive-it.org/22098/2025-05-01T17:13:42Z/http://gigasciencejournal.com/blog/plant-and-animal-genome
version: v1
---

![Plant and Animal Genomes under
construction](http://gigasciencejournal.com/blog/wp-content/uploads/2020/03/EOA21wPUYAEnCJ9-300x225.jpg){.alignright
.size-medium .wp-image-3245 loading="lazy" decoding="async"
srcset="http://gigasciencejournal.com/blog/wp-content/uploads/2020/03/EOA21wPUYAEnCJ9-300x225.jpg 300w, http://gigasciencejournal.com/blog/wp-content/uploads/2020/03/EOA21wPUYAEnCJ9-768x576.jpg 768w, http://gigasciencejournal.com/blog/wp-content/uploads/2020/03/EOA21wPUYAEnCJ9-1024x768.jpg 1024w, http://gigasciencejournal.com/blog/wp-content/uploads/2020/03/EOA21wPUYAEnCJ9.jpg 2048w"
sizes="(max-width: 300px) 100vw, 300px" width="300" height="225"}As
publishers of a lot of plant and animal genomes, the biggest conference
for this research community is the appropriately named [Plant and Animal
Genome Conference (PAG)](https://www.intlpag.org/2020/). We\'ve attended
a number of these giant meetings in their San Diego base, and in recent
years they have been branching out to host satellites in Asia (PAG Asia,
which last year [included a workshop that we participated
in](http://gigasciencejournal.com/blog/pag-asia-2019/)). And we attended
the 28^th^ edition of the meeting this year, which was held as ever in
mid-January.

This year seemed a year in transition -- both physically and
metaphorically -- with the conference hotel for many years (the Town &
Country) being smack in the middle of a much delayed refurbishment. And
the field and talks on show changing rapidly in terms of what are the
norms in genomic research; with increasingly ubiquity, scale and quality
of the outputs on show. This has mostly been driven by the incredibly
rapid advances in technology (such as we\'ve discussed before long
running trends like the [move from short to long
reads](http://gigasciencejournal.com/blog/apple-2-0-delicious-genome/)),
but to catch up with the rapid application of these outputs in
conservation work, genomics-assisted breeding, and genome editing, there
has been a need to scale up education, both to produce a new generation
of genomic scientists, but also the public to understand and make
informed decisions about these new technologies and how they will affect
their lives (see our [Bauhinia Genome
project](http://bauhiniagenome.hk/) as an attempt to do this). As an
area of interest for us it was great to see so many education and
outreach tracks and talks in the meeting. Including [Sarah Evanega from
the Cornell Alliance for Science
keynote](https://intlpag.org/2020/program/plenary-speakers/399-sarah-evanega-video)
on \"Embracing Effective Science Advocacy\".

This year there were 2,951 attendees representing 62 countries, and when
including exhibitors the total attendance was over 3,500. The huge
numbers meaning things were spread over 186 scientific workshops. The
building work not helping things getting around in the venue -- with no
fountain in the fountain court, and a separate off-site location for
some additional tracks. While the venue may have been dusty the keynote
speakers were fresh. Covering and outstanding breadth of topics expected
for such a broad conference. It was great to catch up with lots of old
friends, [Editorial Board
Members](https://academic.oup.com/gigascience/pages/Editorial_Board),
and meeting many of our wonderful authors and reviewers in person.

While the official opening reception wasn\'t until the Sunday evening,
the conference really kicked off with 2 days of pre-meeting workshops
organised by special interest groups. With the [Functional Annotations
of Animal Genomes
(FAANG)](https://www.animalgenome.org/community/FAANG/desc) organising a
full afternoon of talks on the Friday to bring everyone involved up to
speed with the current situation in the many global projects under the
FAANG umbrella. Followed on the Saturday by a series of parallel
workshops on a wide variety of topics.

In the Development and Application of Genome Engineering and Transgenic
Technology for Agriculture session, we were regaled with a tale spanning
two decades by Dr James Dale (Centre for Tropical Crops and
Biocommodities) describing how they are helping prevent vitamin A
deficiency in Uganda by the generation of a transgenic cooking banana
high in vitamin A, which is aimed to be commercially released in 2022
assuming it passes all regulatory reviews.  According to Markita Landry
(University of California Berkeley), the process of delivering genetic
materials into mature plants can now be performed using carbon
nanotubes, which is faster and cheaper than producing full transgenic
strains of crops. As agriculture is such a big part of the meeting these
topics were also covered in some of the keynotes, [Jack Bobo talking
about](https://intlpag.org/2020/program/plenary-speakers/394-jack-bobo-video)
synthetic biology in food, giving a light hearted and entertaining
plenary on the importance of connecting with the public in the right
ways to ensure we, as scientists, get the right messages across to the
general public. His take home message was don\'t tell people the facts,
no-one likes to be told what to think, instead teach people how to
discover the facts. And a great example of this was the \"Modified,\"
retrofitted food truck in the hotel lobby that was serving free tastings
of genetically modified, with a side of science communication, allowing
you to interact and talk to many of the presenting scientists at the
meeting.

> Big rush to grab the GMO papaya parfait and smoothies at the
> [@eat_modified](https://twitter.com/eat_modified?ref_src=twsrc%5Etfw)
> food truck after the great plug from
> [@Sarah_Evanega](https://twitter.com/Sarah_Evanega?ref_src=twsrc%5Etfw)
> [\#PAGXVIII](https://twitter.com/hashtag/PAGXVIII?src=hash&ref_src=twsrc%5Etfw)
> keynote [pic.twitter.com/x8CIX81nd4](https://t.co/x8CIX81nd4)
>
> --- BauhiniaGenome (@BauhiniaGenome) [January 13,
> 2020](https://twitter.com/BauhiniaGenome/status/1216780547684331520?ref_src=twsrc%5Etfw)

The [National Center for Biotechnology Information
(NCBI)](https://www.ncbi.nlm.nih.gov/) was well represented at PAG this
year with speakers in a variety of sessions on the various services and
tools they provide to the genomics communities, including a presentation
by Terence Murphy of the use of Stand-Alone pGap tool. The prokaryotic
genome annotation pipeline (pGap) tool is openly [available in
github](https://github.com/ncbi/pgap/wiki) for anyone to download and
use on their own systems, it includes both abinitio protein coding
region predictions with geneMark as well as by homology based on both
BLAST and HMM profiles. This allows users to identify various erroneous
features in genome annotations prior to submission to GenBank.

Evgeny Zbodnov (SIB, EZlab.org) described the latest version of the
BUSCO tool used to assess the completeness of genome assemblies.
[BUSCOv4](https://busco.ezlab.org/) now uses a different prediction
software to find predicted genes within genome assemblies, and as such
is now able to handle prokaryotic genomes as well. As we publish so many
genomes presenting BUSCO scores we and other journals will need to start
encouraging our authors to upgrade to the new version.

While the field of genomics was still the main focus of many of the
presentations, there was a noticeable number of talks about phenotypic
aspects of plants with a lot of studies utilising imaging, both of above
ground and of roots (image- from W129 Comprehensive Above and below
Ground 3D Phenomics for Grasses, Mao Li (Donald Danforth Plant Science
Center)). Ian Stavness (University of Saskatchewan) in the Plant
Phenotypes session also presented on the use of drones for imaging
entire fields of crops. Another interesting application of genomics on
display was ancient DNA, utilized in a number of conservation and
evolution talks, as well as the excellent keynote from field pioneer
Eske Willerslav.

The Vertebrate Genome Project (VGP) workshop spanned the whole [final
day
workshop](https://static1.squarespace.com/static/5963d1fa9de4bb12177a7f48/t/5e1e700c408e262d95873018/1579053069163/G10K-VGP+Jan+2020+Workshop+Agenda.pdf)
with a packed room at the other venue for the conference. Workshop and
VGP Chair Erich Jarvis gave the introductions, he explained the history
of the VGP and how it fits into the larger ecosystem of big genome
projects like G10K. The VGP has released 101 complete genomes from their
[Genome Ark website](https://vgp.github.io/) 2019 and are on target to
release 260 in 2020, but still seeking additional financial support to
achieve that goal. The group currently has 11 manuscripts in preparation
to mark the completion of these phase1 genomes, and we\'ve already
published \"platinum grade\" and VGP listed genomes including the [barn
swallow](https://doi.org/10.1093/gigascience/giy142).

As a useful gathering of the VGP community before their big yearly
meeting in the summer, many of the key members were present and
presented updates on sample procurement and preparation, the latest in
sequencing technology (with benchmarking), Kerstin Howe (Sanger)
presenting a \"little shop of assembly curation horrors\", and then some
updates on discoveries and outputs, and potential future developments.
The [Darwin Tree of Life Project](https://www.darwintreeoflife.org/) was
present and gave some lessons learned from their regional (UK)
perspective of systematically producing and disseminating high quality
genomes. One of the new projects presented that really showcase where
this new era of genomics is going to was Benedict Paten\'s (UCSC) talk
on a [new \"Human Pangenome
Project\"](http://Human%20Pangenome%20Reference%20Sequence%20Project)
refurbishing and viewing in a new way the human reference sequence.
Aiming to sequence up to 350 diverse human genomes using
state-of-the-art technologies to incorporate high-quality sequences that
are more broadly representative than the current human reference.
Especially since we are finally in [an era of \"telomere-to-telomere\"
assemblies](https://www.biorxiv.org/content/10.1101/735928v3). It was an
exciting end to the meeting, and we look forward to see what
developments in the plant and animal genome world will be underway when
the conference is ready for its 29^th^ edition in its promised
completely upgraded shiny and new venue next year.

Scott Edmunds, *GigaScience*\
Chris Hunter, GigaDB

The post [Under Construction: Plant and Animal Genomes Get a
Refurb](http://gigasciencejournal.com/blog/plant-and-animal-genome/){rel="nofollow"}
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